Two studies presented May 2-5 at the Digestive Disease Week conference in Chicago have identified potential risk factors associated with early-onset colorectal cancer, according to a May 13 Medscape report.
The first study, led by researchers from Newark, N.J.-based New York Medical College at Saint Michael’s Medical Center, found that inflammatory bowel disease, obesity and family history were associated with an increased risk of early-onset colorectal cancer. The team also identified a phenotype linked to an increased risk among individuals ages 18-49.
Other risk factors identified in the study included: metabolic syndrome, diabetes, hepatic steatosis, microcytosis, low ferritin, elevated C-reactive protein, increased red cell distribution width, low high-density lipoprotein, hypertriglyceridemia and thrombocytosis.
The second study, led by researchers at Kaiser Permanente San Francisco Medical Center, found an association between a history of oral antibiotic use and an increased risk of colorectal adenomas among individuals age 50 or younger.
The risk of developing early-onset colorectal adenomas increased with a history of oral antibiotic use and peaked among individuals with a history of seven to nine courses and within five to less than eight years since antibiotic exposure.
Read the full Medscape report here.
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