Cleveland Clinic team develops early-onset colon cancer risk score

Cleveland Clinic researchers have developed a new score to predict the colorectal cancer risk of patients under the age of 45, the age at which current guidelines recommend screening to begin.

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The score takes into account four known risk factors associated with early-onset colorectal cancer and precancerous polyps: family history, body mass index, sex and smoking, according to a March 3 news release from the health system. 

Patients with a score equal to or greater than 9 have a more than 14% likelihood of developing cancer or having an advanced precancerous lesion. The score enables physicians to recommend additional screening when necessary, the release said. 

Researchers published more about the score’s development and validation Feb. 13 in Digestive Diseases and Sciences.

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