Cancer trial enrollment at Kaiser Permanente reflects region’s patient population

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Oakland, Calif.-based Kaiser Permanente researchers found that the demographic makeup of patients enrolled in the health system’s cancer clinical trials closely resembles its broader cancer patient population, according to a study published Sept. 17 in JAMA Network Open.

Researchers analyzed data from Kaiser Permanente Northern California’s cancer registry, which included almost 98,000 patients treated for cancer between 2015 and 2022. Of those patients, 1.4% enrolled in a clinical trial. 

Here are five things to know:

  1. Black patients made up 6.8% of the registry and 6.5% of trial enrollees, while Latino patients made up 13.6% and 12.7%, and Asian patients made up 16.1% and 15.2%, respectively.

  2. Female patients made up 58.2% of the registry and 60% of trial enrollees, while male patients made up 41.7% and 40%, respectively.

  3. Non-English speakers made up 7.1% of the registry but just 4.7% of trial enrollees.

  4. Patients from socioeconomically deprived neighborhoods made up 17% of the registry and 13.7% of enrollees.

  5. To improve enrollment further, Kaiser Permanente Northern California medical sites are piloting a centralized prescreening program that uses EHR data to generate eligibility lists and deliver them directly to physicians.

Read the full study here.

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