Only 19.6% of oncology practices accounted for 80.5% of cancer clinical trial enrollments between 2011 and 2024, according to a study published Oct. 6 in JAMA Network Open.
Researchers from Dallas-based University of Texas Southwestern Medical Center analyzed data from the Flatiron Health Research Database on 205,743 patients with advanced or metastatic cancer treated by 1,664 physicians at 107 oncology practices across the U.S. between 2011 and 2024 to assess factors associated with trial participation.
Here are three notes from the study:
- The percentage of cancer patients participating in clinical trials rose from 3.9% in 2011 to 6.8% in 2024. Overall, 5.2% of cancer patients participated in a clinical trial over the study period.
- Of the 1,664 physicians included in the study, 23.4% accounted for 83.6% of all trial enrollments, while 29.7% of physicians never enrolled a patient in a trial.
- Cancer patients were more likely to enroll in a trial if their physician treated fewer types of cancer, had enrolled other patients in trials in the previous two years and if their practice was highly engaged in research.
Cancer patients were less likely to enroll in a trial if they received care at a practice that served more patients with low socioeconomic status.
Read the full study here.
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