Research

Most patients with advanced pancreatic cancer treated with daraxonrasib will see the drug lose its effect, and researchers are starting to identify why, according to a Sept. 30 report in The New York Times. The FDA approved Revolution Medicines’ daraxonrasib…

Pittsburgh-based UPMC Hillman Cancer Center has opened the Mario Lemieux Microbiome Innovation Center, to study the microbiome’s role in cancer prevention, treatment response and patient outcomes. The center  was established with a $5 million gift from the Mario Lemieux Foundation,…

Buffalo, N.Y.-based Roswell Park Comprehensive Cancer Center has dosed the first patient in a phase 1 trial of an AI-designed CAR T-cell therapy for ovarian cancer. The therapy, GB-5267, was developed by Somerville, Mass.-based Generate Biomedicines, according to an Oct.…

HHS has launched its third clinical trial initiative in six months, this time aimed at trial design, site capacity and data infrastructure. The Advanced Research Projects Agency for Health’s Simulation-augmented, Real-time Platform Adaptive Seamless Trials program, or SURPASS, aims to…

St. Louis-based WashU Medicine investigators received an $11.7 million NIH grant to study the role of inflammation in myeloproliferative neoplasms, a group of blood cancers. The grant from the National Heart, Lung, and Blood Institute will support four major research…

Breast and prostate cancer incidence is rising among people of every race and ethnicity in the U.S., while lung cancer incidence and death rates are dropping sharply, according to the CDC’s “Annual Report to the Nation on the Status of…

Researchers at Aurora-based University of Colorado Anschutz Cancer Center have secured a three-year Defense Department grant totaling nearly $1.75 million to develop a therapy for treatment-resistant thyroid cancers.  The DOD Impact Award went to Rebecca Schweppe, PhD, Bryan Haugen, MD,…

Duarte, Calif.-based City of Hope researchers have developed a way to modify CAR-T cells after infusion, an approach designed to help the therapy adapt as tumors change. The preclinical study on the technology was published Sept. 7 in Cancer Immunology…

A blood test correctly identified 87% of stage 1 and 2 pancreatic cancers, according to a study published Sept. 16 in Nature Medicine. For the study, researchers from Duarte, Calif.-based City of Hope tested the PANXEON liquid biopsy in nearly…

A rare inherited gene variant was linked to a 25-fold increase in lung cancer risk, according to a study published Sept. 17 in Science. Researchers at Boston-based Dana-Farber Cancer Institute analyzed genetic data from more than 3.3 million 23andMe research…